Dentists all over the country are switching to Septocaine anesthetic because of it’s more profound and deeper-penetrating effect. Doctors report greater success with their injections and less need for palatal anesthesia because it can diffuse through from the buccal. Septocaine has only been available in the United States for the last few years. But consider for over 20 years, dentists around the world have been injecting Articaine safely and effectively. They’ve proven it in their offices, and it’s been proven in numerous clinical trials. 50 units/box.